For centuries, many people have used fasting—the act of abstaining from all food and drink (except water) for a specified period of time—as a means of “cleaning” out the body. More recently intermittent fasting has become a popular health and weight loss strategy. 

Intermittent fasting refers to various meal timing schedules that cycle between voluntary fasting over a given period and eating. Interestingly, many religions employ forms of intermittent fasting, e.g., Ramadan (Islam), Vrata (Hinduism), Yom Kippur (Judaism), and Fast Sunday (The Church of Jesus Christ of Latter-day Saints).

‌‌‌‌What Is Intermittent Fasting?

There are three methods of intermittent fasting: 

  • Alternate-day fasting 
  • Periodic fasting (e.g., every Sunday or two days fasting per week)
  • Time-restricted feeding

Of these, time-restricted feeding has become the most popular with the 16/8 method being most-widely used. In the 16/8 method, a person will fast for 16 hours each day and eat during an 8-hour window. That can be accomplished by skipping breakfast, having the first meal around noon, and not eating anything after an early dinner. 

The real key to the health benefits of intermittent fasting is what you eat during your eating window. Obviously, it doesn’t work if you binge on excess calories or unhealthy food. If you employ principles of healthful eating during your window then intermittent fasting can be very effective in improving metabolism and promoting weight loss.

The 16/8 method can be tough, so I modify it a bit as I don’t see a problem drinking water, tea, and other non- or low-caloric beverages during the 16-hour fast. Including these beverages during the 16-hour non-feeding window can help reduce hunger levels and encourage the consumption of health-promoting beverages and adequate hydration.

‌‌‌‌What Are The Benefits of Intermittent Fasting?

The benefit of intermittent fasting on weight loss has been demonstrated in controlled clinical trials.1 Best results, however, are obtained in people who are also involved in resistance training (e.g., lifting weights or other strength-training) as that has been shown to improve body composition by decreasing fat mass and at least preserving muscle mass during weight loss.2 Intermittent fasting can also improve blood sugar control and cholesterol levels, but a lot depends on the quality of the food choices.3 

During Ramadan, Muslims fast every day from dawn to sunset. It is a form of intermittent fasting where the feeding window is limited to just before sunrise and just after sunset. Meal and menu planning is critical, but Ramadan-type intermittent fasting can be a very healthful practice. Specifically, in a detailed scientific review, researchers concluded Ramadan-type intermittent fasting is effective in boosting mental function and immune function.4 It has also been shown to be helpful in decreasing body weight and relative fat mass. Although other forms of intermittent fasting (e.g., the 16:8 method) seem to be more effective in improving overall body composition by maintaining muscle mass.5

The risk with this sort of intermittent fast is binge eating after fasting all day. To help prevent this from occurring, I recommend 5 grams of PGX before meals. PGX is a very unique dietary fiber that is clinically proven to promote satiety and help people control food intake to proper portion size.

‌‌‌‌Does Fasting Promote Detoxification?

Yes, fasting is one of the quickest ways to increase the elimination of wastes, promote detoxification, and enhance the healing processes of the body. Although therapeutic fasting is probably one of the oldest known therapies, it has been largely ignored by the scientific community. 

Caution must be used, however, if a person has significant levels of fat-soluble toxins like pesticides, heavy metals (lead, mercury, arsenic, etc.) stored in their fat cells. These sorts of toxins have been shown to be mobilized during a fast and raise blood levels. That could lead to increased toxicity to the brain and nervous system. One of the concerns with strict water fasting is that a person would not be getting the nutrients needed to keep the detoxification system running. The liver needs a steady supply of protein, vitamins, and minerals to produce the substances that make detoxification happen. For this reason, I prefer juice fasts and detoxification diets to a strict water fast. And, whether you do a water fast, juice fast, or detox diet follow the critical guidelines and dietary supplement recommendations for supporting the liver and detoxification reactions.

‌‌‌‌What Is A 10-Day Detox Diet? 

Instead of fasting consider a 10-day detox diet (that ideally includes a 3-day juice fast in the middle). I think this strategy is actually the best approach as it allows for the proper detoxification and elimination of toxic compounds. The diet should be at a caloric deficit. We want fat cells to break down and release stored toxins, but we don’t want to overwhelm our detoxification system. 

What Is A Juice Fast?

By strict definition, during a fast only water is consumed. If you are drinking fresh fruit or vegetable juice, this practice is technically known as an elimination diet rather than a fast, but let’s just call it a “juice fast” for simplicity. In my opinion, most healthy people do not need to go on a strict water fast to aid in detoxification. Instead, a three-to-five-day fresh fruit and vegetable juice fast actually provides the greatest benefit. An alternative to drinking fresh fruit or vegetable juice is to use dehydrated powdered “greens” drink mixes such as those containing spirulina, wheatgrass juice, or barley greens.

Only fresh fruit and vegetable juices (ideally prepared from organic produce) or reconstituted powdered drink mixes should be consumed for three to five days. Generally drink four 8- to 12-ounce glasses throughout the day.

Virtually any fresh juice provides support for detoxification; however, some of the better juices to consume during a fast include juice from lemons, beets, carrots, kale, celery, and sweet potatoes. You can sweeten if necessary, with apple and you can spice it up with ginger or turmeric. In addition to the fresh juice, pure water should also be consumed. The quantity of water should be dictated by thirst, but at least four 8-ounce glasses should be consumed every day during the fast.

“Do’s And Don’ts'' Of A Detox Diet:

Do's Don'ts

Vegetables especially leafy greens

Refined processed foods

Legumes (beans and lentils)

High sugar foods and beverages

Whole fruit especially berries

Alcohol and diet sodas

Non-gluten grains

Wheat and gluten

Low-mercury fish such as wild salmon, smaller species of ocean fish like sardines and herring, and rainbow trout

High-mercury fish such as swordfish, marlin, orange roughie, shark, and larger tuna.

Organic, grass-fed meat and dairy (optional)

Grain-fed and non-organic dairy

Nuts and seeds

Potato and corn chips

Good oils like oliveavocadococonut, and flaxseed

Bad oils like corn, safflower, soy, margarine, and shortening

Tips To Support A 10-day Detox Diet:

  • Reduce calorie intake to approximately 1,200 calories per day to safely release stored toxins.
  • Include these foods regularly as they contain the nutrients your body needs to produce and activate the dozens of enzymes involved in the various phases of detoxification:
    • Beets, celery, and carrots.
    • Cabbage-family vegetables such as broccoli, kale, Brussels sprouts, and cabbage.
    • Green foods like green leafy salads, wheatgrass juice, dehydrated barley grass juice, chlorella, and spirulina.
  • Follow the guidelines below for dietary supplements to support detoxification.

‌‌‌‌What Are Some Important Guidelines For A Fast Or Detox Diet?

It is extremely important to support detoxification reactions. This goal is partly done by either a fresh juice fast or a 10-day detox diet over a water fast, but I also believe that it is important to provide additional nutritional support when needed during a fast, stored toxins in our fat cells are released into the system. Here are some critical general guidelines:

  • No coffee, soft drinks, sports drinks, or any other processed beverage should be taken. Herbal teas can be quite supportive of a fast, but they should not be sweetened with anything other than perhaps stevia or allulose.
  • Drink plenty of pure, clean water.
  • Exercise is not usually encouraged while fasting. It is a good idea to conserve energy and allow maximal healing. Short walks or light stretching are useful, but heavy workouts tax the system and inhibit repair and elimination.
  • Cleansing the skin with lukewarm water is encouraged, but extremes of temperature can be tiring. Deodorants, soaps, sprays, detergents, synthetic shampoos, and exposure to other chemicals should be avoided. These only hinder elimination and add to the body’s detoxification and elimination burden.
  • Rest is one of the most important aspects of a fast. A nap or two during the day is recommended. Less sleep will usually be required at night since daily activity is lower.
  • Body temperature usually drops during a fast, as do blood pressure, pulse, and respiratory rate—all measures of the slowing of the metabolic rate of the body. It is important, therefore, to stay warm.

‌‌‌‌What Dietary Supplements Should I Take to Support Health During a Fast or Detox Diet?

It is important to provide the liver with exceptional support to allow it to perform its vital detoxification role, especially during a fast or dietary detox. Without proper support, detoxification can go awry and increase the risk for serious health issues.

Foundation Supplements

  1.  High potency multiple vitamin and mineral formula
  2. Vitamin D3: 2,000 to 4,000 IU per day
  3. Fish oil providing EPA+DHA+DPA 1,000 to 2,000 mg per day
  4. Grapeseed or pine bark extract: 150 to 300 mg per day

Additional Recommendations

  1. Vitamin C: 500 to 1,000 mg per day
  2. Soluble fiber (PGX®, apple pectin, guar gum, etc.): 3 to 5 grams daily
  3. N-acetylcysteine (NAC): 500 to 1,000 mg per day
  4. Lipotropic agents. Choose one of the following: 
  5. Alpha-lipoic acid: 200 to 600 mg per day
  6. Milk thistle. Choose one of the following:
  • Siliphos®: 240 to 360 mg per day
  • Milk thistle (Silybum marianum) extract (standardized to contain 80% silymarin): 100 to 200 mg three times daily

In addition, many major brands offer specific dietary formulas to support detoxification that include many of the compounds listed above.

References:

  1. Fanti M, Mishra A, Longo VD, Brandhorst S. Time-Restricted Eating, Intermittent Fasting, and Fasting-Mimicking Diets in Weight Loss. Curr Obes Rep. 2021 Jan 29. 
  2. Sandoval C, Santibañez S, Villagrán F. Effectiveness of intermittent fasting to potentiate weight loss or muscle gains in humans younger than 60 years old: a systematic review. Int J Food Sci Nutr. 2021 Jan 4:1-12
  3. Borgundvaag E, Mak J, Kramer CK. Metabolic impact of intermittent fasting in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of interventional studies. J Clin Endocrinol Metab. 2020 Dec 15:dgaa926.
  4. Cherif A, Roelands B, Meeusen R, Chamari K. Effects of Intermittent Fasting, Caloric Restriction, and Ramadan Intermittent Fasting on Cognitive Performance at Rest and During Exercise in Adults. Sports Med. 2016 Jan;46(1):35-47. doi: 10.1007/s40279-015-0408-6. PMID: 26438184.
  5. Correia JM, Santos I, Pezarat-Correia P, Silva AM, Mendonca GV. Effects of Ramadan and Non-ramadan Intermittent Fasting on Body Composition: A Systematic Review and Meta-Analysis. Front Nutr. 2021 Jan 26;7:625240.